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AI-designed antibodies promise big boost to drug development

University of Washington team uses generative AI tool to create new functional cancer antibodies

A team led by Nobel Prize-winning scientist David Baker has used an artificial intelligence tool to create new functional antibodies in a breakthrough that could speed up drug development using the cutting-edge technology.

In a study published on Wednesday in Nature, researchers at the University of Washington showed how a generative AI model could be used to design entirely new antibodies — proteins that our immune systems produce to block infections — from scratch.  

The pharmaceutical industry widely uses antibodies to create drugs, such as for cancer and coronaviruses. But creating the proteins using computers has been a long-standing challenge in drug design.

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