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Patients on diabetes drugs less likely to develop dementia, research finds

More trials urged as part of effort to slow cognitive declines with existing medicines

Patients who took certain drugs to combat type 2 diabetes proved less likely to develop dementia, according to research that suggests brain disorders could be tackled with therapies devised for other uses. 

The study of more than 200,000 people found that rates of Alzheimer’s disease for those who took inhibitors for sodium-glucose cotransporter-2 (SGLT-2), to lower their blood sugar, were more than a third lower than for those on another anti-diabetes medication. 

While the observational survey conducted in South Korea does not demonstrate a causal link between SGLT-2 inhibitors and prevention of dementia, more extensive trials of some diabetes drugs such as Novo Nordisk’s Ozempic for similar uses are already under way.

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