Rare cancers need a Silicon Valley approach to investment | 攻克罕见癌症需要硅谷式的投资方法 - manbetx20客户端下载
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医疗科学

Rare cancers need a Silicon Valley approach to investment
攻克罕见癌症需要硅谷式的投资方法

Innovative models can drive funding for research on neglected, less survivable diseases
加斯特:创新模式可以推动对被忽视的顽固癌症研究提供资金。
The writer is a former president of Imperial College London
本文作者是伦敦帝国理工学院(Imperial College London)前校长
During my time at Imperial College London, Stanford, MIT and Pennsylvania’s Lehigh, I have seen the positive impact of the work done by some of the greatest researchers in the world and how it can improve people’s lives. But the benefits of such work came into starker view for me when I was diagnosed with pancreatic cancer in 2021.
在伦敦帝国理工学院、斯坦福大学(Stanford)、麻省理工学院(MIT)和宾夕法尼亚州理海大学(Lehigh)工作期间,我看到了世界上一些最伟大的研究人员所做的工作产生的积极影响,以及它们如何改善人们的生活。但当我在2021年被诊断出患有胰腺癌时,这种工作的好处对我来说变得更加明显。
Under-investment in research on this disease has contributed to a shocking survival rate. Sadly, there are several other cancers — including those of the brain, liver, stomach, oesophagus and lung — that have also been left behind, with dismal survival rates below 25 per cent. Known as less survivable cancers, these make up 20 per cent of cases in the UK, yet cause 40 per cent of the deaths.
对这种疾病的研究投资不足,导致该病患者存活率令人震惊。可悲的是,还有其他几种癌症——包括脑癌、肝癌、胃癌、食道癌和肺癌——也被抛在了后面,存活率低于25%。这些癌症被称为存活率较低的癌症,占英国病例的20%,但却导致了40%的死亡。
Too often, researchers and funders shift their focus elsewhere. And while large projects and research groups have made tremendous progress in many other areas of cancer, now is the time to focus on the recalcitrant and less survivable varieties where the big breakthroughs are yet to be made.
研究人员和资助者经常将注意力转移到其他地方。虽然大型项目和研究小组在癌症的许多其他领域取得了巨大进展,但现在是时候把重点放在尚未取得重大突破、存活率较低的顽固疾病上了。
The good news is that investment makes a difference. The doubling of government and research funders’ investment in leukaemia has meant that survival rates are now four times higher than in the 1970s, helping to deliver better diagnostic tools and treatments such as highly targeted drugs. The UK aims to lead the world in research, development and innovation. To do so, we must address the woeful lack of research funding and poor outcomes for the less survivable cancers. 
好消息是,投资带来了改变。政府和研究资助者对白血病的投资翻了一番,使得现在白血病患者的存活率是上世纪70年代的4倍,投资有助于提供更好的诊断工具和治疗方法,比如高度靶向的药物。英国的目标是在研究、开发和创新方面引领世界。要做到这一点,我们必须解决严重缺乏研究资金和对存活率较低的癌症治疗效果不佳的问题。
In March, the government launched a plan to “cement the UK’s place as a science and technology superpower by 2030”, suggesting “testing different models of fun